Salirasib | B2097

Salirasib is a potent Inhibitor of active Ras proteins. It displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.

Salirasib is a potent Inhibitor of active Ras proteins. It displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.

B2097 | Salirasib DataSheet

Alternate Name/Synonyms: 2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid; FTS

Appearance: White solid

Formulation: N/A

CAS Number: 162520-00-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₃₀O₂S

Molecular Weight: 358.54

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent Inhibitor of active Ras proteins

MDL Number: MFCD00467723

PubChem CID: 5469318

SMILES: CC(=CCCC(=CCCC(=CCSC1=CC=CC=C1C(=O)O)C)C)C

InChi: InChI=1S/C22H30O2S/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H,23,24)/b18-11+,19-15+

InChi Key: WUILNKCFCLNXOK-CFBAGHHKSA-N