Description
SAR260301 is a potent and selective Class I phosphatidylinositol-3-kinase-β (PI3K-β) specific inhibitor with an IC₅₀ of 52 nM for this isoform. SAR260301 displays improved physicochemical and in vitro pharmacokinetic properties.
SAR260301 is a potent and selective Class I phosphatidylinositol-3-kinase-β (PI3K-β) specific inhibitor with an IC₅₀ of 52 nM for this isoform. SAR260301 displays improved physicochemical and in vitro pharmacokinetic properties.
Alternate Name/Synonyms: (S)-2-(2-(2-methylindolin-1-yl)-2-oxoethyl)-6-morpholinopyrimidin-4(3H)-one
Appearance: Crystaline solid
Formulation: N/A
CAS Number: 1260612-13-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₉H₂₂N₄O₃
Molecular Weight: 354.4
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective Class I phosphatidylinositol-3-kinase-β (PI3K-β) specific inhibitor
MDL Number: MFCD27987912
PubChem CID: 49854424
SMILES: CC1CC2=CC=CC=C2N1C(=O)CC3=NC(=O)C=C(N3)N4CCOCC4
InChi: InChI=1S/C19H22N4O3/c1-13-10-14-4-2-3-5-15(14)23(13)19(25)11-16-20-17(12-18(24)21-16)22-6-8-26-9-7-22/h2-5,12-13H,6-11H2,1H3,(H,20,21,24)/t13-/m0/s1
InChi Key: UAXHPOBBKRWJGA-ZDUSSCGKSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |