SBHA | 2202

SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC₅₀ = 0.25 μM) and HDAC3 (IC₅₀ = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines.

SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC₅₀ = 0.25 μM) and HDAC3 (IC₅₀ = 0.30 μM).

2202 | SBHA DataSheet

Alternate Name/Synonyms: Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N'-dihydroxyoctanediamide

Appearance: White to Off-white Solid

Formulation: N/A

CAS Number: 38937-66-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₈H₁₆N₂O₄

Molecular Weight: 204.22

Cell-Permeable?: Yes

Purity: ≥95% by TLC

Solubilities: H2O (100 mM) or DMSO (100 mM)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent HDAC inhibitor

MDL Number: MFCD00192455

PubChem CID: 5173

SMILES: C(CCCC(=O)NO)CCC(=O)NO

InChi: InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)

InChi Key: IDQPVOFTURLJPT-UHFFFAOYSA-N