SBI-797812 | B2746

SBI-797812 is a novel nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 acts as a “super catalyst” that more efficiently generates NMN (nicotinamide mononucleotide).

SBI-797812 is a novel nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 acts as a “super catalyst” that more efficiently generates NMN (nicotinamide mononucleotide).

B2746 | SBI-797812 DataSheet

Alternate Name/Synonyms: 1-(4-(((1R,5S)-8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)sulfonyl)phenyl)-3-(pyridin-4-ylmethyl)urea

Appearance: Crystalline solid

Formulation:

CAS Number: 2237268-08-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₂N₄O₄S

Molecular Weight: 402.47

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A novel NAMPT activator

MDL Number:

PubChem CID: 135222620

SMILES: C1CC2CN(CC1O2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)NCC4=CC=NC=C4

InChi: InChI=1S/C19H22N4O4S/c24-19(21-11-14-7-9-20-10-8-14)22-15-1-5-18(6-2-15)28(25,26)23-12-16-3-4-17(13-23)27-16/h1-2,5-10,16-17H,3-4,11-13H2,(H2,21,22,24)

InChi Key: KTSOHNHLOLGQCY-UHFFFAOYSA-N