Scriptaid | 1605

A relatively non-toxic Inhibitor of histone deacetylase (HDAC). Facilitates transcriptional activation (TGF-β/Smad4) in both stable and transient receptor assays in a concentration-dependent manner. At ~2 µg/ml (6-8 µM) concentrations, results in a greater than 100-fold increase in histone acetylation in PANC-1 cells.

Scriptaid is a a relatively non-toxic Inhibitor of histone deacetylase (HDAC). Facilitates transcriptional activation (TGF-β/Smad4) in both stable and transient receptor assays in a concentration-dependent manner.

1605 | Scriptaid DataSheet

Alternate Name/Synonyms: N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 287383-59-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₈N₂O₄

Molecular Weight: 326.35

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (100 mM)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A HDAC inhibitor

MDL Number: MFCD00386477

PubChem CID: 5186

SMILES: C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO

InChi: InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9,24H,1-3,10-11H2,(H,19,21)

InChi Key: JTDYUFSDZATMKU-UHFFFAOYSA-N