Senicapoc | B2390

Senicapoc (ICA-17043) is a potent and selective Gardos channel blocker (IC₅₀ = 11 nM). Senicapoc (ICA-17043) could be a potential drug for the prevention and treatment of hemolysis-associated complications in sickle cell anemia. Also acts as an anti-malarial agent.

Senicapoc (ICA-17043) is a potent and selective Gardos channel blocker (IC₅₀ = 11 nM). Senicapoc (ICA-17043) could be a potential drug for the prevention and treatment of hemolysis-associated complications in sickle cell anemia. Also acts as an anti-malarial agent.

B2390 | Senicapoc DataSheet

Alternate Name/Synonyms: 2,2-bis(4-fluorophenyl)-2-phenylacetamide, ICA17043, ICA-17043

Appearance: Crystalline solid

Formulation:

CAS Number: 289656-45-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Yes

Molecular Formula: C₂₀H₁₅F₂NO

Molecular Weight: 323.34

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: a potent Gardos Channel Inhibitor

MDL Number:

PubChem CID: 216327

SMILES: C1=CC=C(C=C1)C(C2=CC=C(C=C2)F)(C3=CC=C(C=C3)F)C(=O)N

InChi: InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13H,(H2,23,24)

InChi Key: SCTZUZTYRMOMKT-UHFFFAOYSA-N