Description
Senicapoc (ICA-17043) is a potent and selective Gardos channel blocker (IC₅₀ = 11 nM). Senicapoc (ICA-17043) could be a potential drug for the prevention and treatment of hemolysis-associated complications in sickle cell anemia. Also acts as an anti-malarial agent.
Senicapoc (ICA-17043) is a potent and selective Gardos channel blocker (IC₅₀ = 11 nM). Senicapoc (ICA-17043) could be a potential drug for the prevention and treatment of hemolysis-associated complications in sickle cell anemia. Also acts as an anti-malarial agent.
Alternate Name/Synonyms: 2,2-bis(4-fluorophenyl)-2-phenylacetamide, ICA17043, ICA-17043
Appearance: Crystalline solid
Formulation:
CAS Number: 289656-45-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: Yes
Molecular Formula: C₂₀H₁₅F₂NO
Molecular Weight: 323.34
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: a potent Gardos Channel Inhibitor
MDL Number:
PubChem CID: 216327
SMILES: C1=CC=C(C=C1)C(C2=CC=C(C=C2)F)(C3=CC=C(C=C3)F)C(=O)N
InChi: InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13H,(H2,23,24)
InChi Key: SCTZUZTYRMOMKT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |