Description
Sesamolin is a furofuran lignan extracted from sesame seeds. It displays beneficial biological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. Also known to inhibit lipid peroxidation in rat liver and kidney. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt′s lymphoma cells, presenting a potential immunotherapeutic value for cancer treatment. In addition, it has been demonstrated that sesamolin inhibits β-secretase, presenting an important role for prevention of dementia by daily consumption.
Sesamolin is a furofuran lignan extracted from sesame seeds. It displays beneficial biological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. Also known to inhibit lipid peroxidation in rat liver and kidney. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt′s lymphoma cells, presenting a potential immunotherapeutic value for cancer treatment. In addition, it has been demonstrated that sesamolin inhibits β-secretase, presenting an important role for prevention of dementia by daily consumption.
Alternate Name/Synonyms: 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole
Appearance: White to off-white solid
Formulation:
CAS Number: 526-07-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₁₈O₇
Molecular Weight: 370.35
Cell-Permeable?: TRUE
Purity: ≥97%
Solubilities: ~10 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A biologically active furofuran lignan
MDL Number:
PubChem CID: 101746
SMILES: C1C2C(COC2OC3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6
InChi: InChI=1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
InChi Key: ZZMNWJVJUKMZJY-AFHBHXEDSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |