Sesamolin | B2780

Sesamolin is a furofuran lignan extracted from sesame seeds. It displays beneficial biological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. Also known to inhibit lipid peroxidation in rat liver and kidney. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt′s lymphoma cells, presenting a potential immunotherapeutic value for cancer treatment. In addition, it has been demonstrated that sesamolin inhibits β-secretase, presenting an important role for prevention of dementia by daily consumption.

Sesamolin is a furofuran lignan extracted from sesame seeds. It displays beneficial biological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. Also known to inhibit lipid peroxidation in rat liver and kidney. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt′s lymphoma cells, presenting a potential immunotherapeutic value for cancer treatment. In addition, it has been demonstrated that sesamolin inhibits β-secretase, presenting an important role for prevention of dementia by daily consumption.

B2780 | Sesamolin DataSheet

Alternate Name/Synonyms: 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole

Appearance: White to off-white solid

Formulation:

CAS Number: 526-07-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₈O₇

Molecular Weight: 370.35

Cell-Permeable?: TRUE

Purity: ≥97%

Solubilities: ~10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A biologically active furofuran lignan

MDL Number:

PubChem CID: 101746

SMILES: C1C2C(COC2OC3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6

InChi: InChI=1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

InChi Key: ZZMNWJVJUKMZJY-AFHBHXEDSA-N