Shikonin | B1056

Shikonin is a naturally occurring naphthoquinone derivative that displays anti-inflammatory and antitumor properties. Displays anti-angiogenic properties by inhibition of proliferation and migration of endothelial cells, blocking integrin αvβ3 expression,etc. Shikonin also inhibits cancer cell glycolysis by targeting tumor pyruvate kinase M2 (PKM2).

Shikonin is a naturally occurring naphthoquinone derivative that displays anti-inflammatory and antitumor properties. Displays anti-angiogenic properties by inhibition of proliferation and migration of endothelial cells, blocking integrin αvβ3 expression,etc. Shikonin also inhibits cancer cell glycolysis by targeting tumor pyruvate kinase M2 (PKM2).

B1056 | Shikonin DataSheet

Alternate Name/Synonyms: (±)-Alkannin, (±)-Shikalkin, (±)-Shikonin, (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone

Appearance: Red to brown solid

Formulation: N/A

CAS Number: 517-89-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₆O₅

Molecular Weight: 288.3

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A pyruvate kinase M2 (PKM2) inhibitor

MDL Number: MFCD00016668

PubChem CID: 5208

SMILES: CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C

InChi: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3

InChi Key: NEZONWMXZKDMKF-UHFFFAOYSA-N