SLC36A2 Antibody | 8341

SLC36A2 Antibody | 8341 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: SLC36A2 antibody was raised against a 15 amino acid peptide near the amino terminus of human SLC36A2.
The immunogen is located within amino acids 30 - 80 of SLC36A2.

Research Area: Homeostasis, Neuroscience

Tested Application: E, WB

Application: SLC36A2 antibody can be used for detection of SLC36A2 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: SLC36A2 antibody is human specific. SLC36A2 is predicted to not cross-react with other members of the SLC36 protein family.

Positive Control 1: Cat. No. 1319 - Human Stomach Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 53 kDa
Observed: 52 kDa

Validation: N/A

Isoform: N/A

Purification: SLC36A2 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLC36A2 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLC36A2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Solute carrier family 36 (proton/amino acid symporter) member 2, proton-coupled amino acid transporter 2, PAT2, TRAMD1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLC36A2 is a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline (1, 2) . Both SLC36A2 and its paralog SLC36A1 are expressed in neurons, but SLC36A2 localizes to the endoplasmic reticulum and recycling endosome, while SLC36A1 is expressed in the lysosome (2) . SLC36A2 is thought to contribute to neuronal transport and sequestration of amino acids such as glycine, alanine, and proline (2) . Mutations in this gene are associated with iminoglycinuria and hyperglycinuria (3) .