Description
A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.
Sodium butyrate is a short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC).
1609 | Sodium butyrate DataSheet
Alternate Name/Synonyms: Butyric acid, Sodium salt, NaB
Appearance: White solid
Formulation: N/A
CAS Number: 156-54-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄H₇O₂ . Na
Molecular Weight: 110.1
Cell-Permeable?: Yes
Purity: ≥99% by HPLC
Solubilities: H₂O (100 mM)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A HDAC inhibitor
MDL Number: MFCD00002816
PubChem CID: 5222465
SMILES: CCCC(=O)[O-].[Na+]
InChi: InChI=1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChi Key: MFBOGIVSZKQAPD-UHFFFAOYSA-M
Additional Information
Storage Condition: |
RT |
Shipping Condition: |
RT |
Shelf Life: |
24months |