Sodium butyrate | 1609

A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.

Sodium butyrate is a short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC).

1609 | Sodium butyrate DataSheet

Alternate Name/Synonyms: Butyric acid, Sodium salt, NaB

Appearance: White solid

Formulation: N/A

CAS Number: 156-54-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄H₇O₂ . Na

Molecular Weight: 110.1

Cell-Permeable?: Yes

Purity: ≥99% by HPLC

Solubilities: H₂O (100 mM)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A HDAC inhibitor

MDL Number: MFCD00002816

PubChem CID: 5222465

SMILES: CCCC(=O)[O-].[Na+]

InChi: InChI=1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1

InChi Key: MFBOGIVSZKQAPD-UHFFFAOYSA-M