Description
Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL). It has been shown to inhibit growth and induce apoptosis of various cancer cells. Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic mitochondrial death pathway.
Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL). It has been shown to inhibit growth and induce apoptosis of various cancer cells. Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic mitochondrial death pathway.
Alternate Name/Synonyms: Solasodine-L-rhamnosido-D-glucoside (3b,22a,25R)-Spirosol-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(1→2)-O-[6-deoxy-a-L-mannopyranosyl-(1→4)]-b-D-glucopyranoside
Appearance: White to of-white solid
Formulation: N/A
CAS Number: 20311-51-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₄₅H₇₃NO₁₅
Molecular Weight: 868.07
Cell-Permeable?: yes
Purity: ≥95%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An anticancer agent
MDL Number: N/A
PubChem CID: 73611
SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)NC1
InChi: InChI=1S/C45H73NO15/c1-19-9-14-45(46-17-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(53)34(51)32(49)22(4)56-41)37(54)38(29(18-47)58-42)59-40-35(52)33(50)31(48)21(3)55-40/h7,19-22,24-42,46-54H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1
InChi Key: MBWUSSKCCUMJHO-ZGXDEBHDSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |