Solamargine | B1586

Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL). It has been shown to inhibit growth and induce apoptosis of various cancer cells. Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic mitochondrial death pathway.

Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL). It has been shown to inhibit growth and induce apoptosis of various cancer cells. Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic mitochondrial death pathway.

B1586 | Solamargine DataSheet

Alternate Name/Synonyms: Solasodine-L-rhamnosido-D-glucoside (3b,22a,25R)-Spirosol-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(1→2)-O-[6-deoxy-a-L-mannopyranosyl-(1→4)]-b-D-glucopyranoside

Appearance: White to of-white solid

Formulation: N/A

CAS Number: 20311-51-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₄₅H₇₃NO₁₅

Molecular Weight: 868.07

Cell-Permeable?: yes

Purity: ≥95%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anticancer agent

MDL Number: N/A

PubChem CID: 73611

SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)NC1

InChi: InChI=1S/C45H73NO15/c1-19-9-14-45(46-17-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(53)34(51)32(49)22(4)56-41)37(54)38(29(18-47)58-42)59-40-35(52)33(50)31(48)21(3)55-40/h7,19-22,24-42,46-54H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1

InChi Key: MBWUSSKCCUMJHO-ZGXDEBHDSA-N