SR-717 Lithium | B3216

SR-717 is a non-nucleotide STING (stimulator of interferon (IFN) genes) agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Displays antitumor activity.

SR-717 is a non-nucleotide STING (stimulator of interferon (IFN) genes) agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Displays antitumor activity.

B3216 | SR-717 Lithium DataSheet

Alternate Name/Synonyms: SR717,lithium 2-(6-(1H-imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate

Appearance: Crystalline solid

Formulation:

CAS Number: 2375421-09-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₈F₂LiN₅O₃

Molecular Weight: 351.19

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A non-nucleotide STING agonist

MDL Number:

PubChem CID: 139434658

SMILES: [Li+].C1=CC(=NN=C1C(=O)NC2=CC(=C(C=C2C(=O)[O-])F)F)N3C=CN=C3

InChi: InChI=1S/C15H9F2N5O3.Li/c16-9-5-8(15(24)25)12(6-10(9)17)19-14(23)11-1-2-13(21-20-11)22-4-3-18-7-22;/h1-7H,(H,19,23)(H,24,25);/q;+1/p-1

InChi Key: ODSAJRWPLSVEHJ-UHFFFAOYSA-M