SRP72 Antibody | 13-852

SRP72 Antibody | 13-852 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: A synthetic peptide of human SRP72

Research Area: Signal Transduction

Tested Application: WB, IHC, IF, Flow

Application: WB: 1:500 - 1:2000
IHC: 1:20 - 1:50
IF: 1:20 - 1:50
Flow: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: Jurkat

Positive Control 3: LO2

Positive Control 4: U-87MG

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 75kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.

Alternate Name: Signal recognition particle subunit SRP72, SRP72, Signal recognition particle 72 kDa protein, SRP72

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP) , a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER) . The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.