SRT1720 | 2772

SRT1720 is a selective SIRT1 activator (EC₅₀ = 0.16 μM). It displays >230-fold less potency against SIRT2 and SIRT3.

SRT1720 is a selective SIRT1 activator (EC₅₀ = 0.16 μM). It displays >230-fold less potency against SIRT2 and SIRT3.

2772 | SRT1720 DataSheet

Alternate Name/Synonyms: N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide

Appearance: Pale brown to dark brown solid

Formulation: N/A

CAS Number: 1001645-58-4

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₃N₇OS.HCl

Molecular Weight: 506.02

Cell-Permeable?: Y

Purity: ≥98% by HPLC

Solubilities: DMSO (>35 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A SIRT1 activator

MDL Number: N/A

PubChem CID: 25232708

SMILES: C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl

InChi: InChI=1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H

InChi Key: DTGRRMPPXCRRIM-UHFFFAOYSA-N