171
Stable Bcl-xL Mouse Embryonic Fibroblast Cell Line | T6081
- SKU:
- 171-T6081-GEN
- Availability:
- IN STOCK
Description
Stable Bcl-xL Mouse Embryonic Fibroblast Cell Line | T6081
The Stable Bcl-xL Mouse Embryonic Fibroblast Cell Line was derived from primary embryonic cells from an 11-d-pregnant Bcl-x heterozygous mouse. After immortalization by transfection of the SV40 large T antigen, the mouse embryonic fibroblasts were transfected with wild-type Bcl-xL cDNA. This stable cell line is able to express B-cell lymphoma-extra-large (Bcl-xL) which is a major regulator of cellular apoptotic signalling by expressing antiapoptotic Bcl-2 proteins. The Stable Bcl-xL Mouse Embryonic Fibroblast Cell Line is a useful model in studying apoptosis regulation of tissue differentiation and homeostasis as well as in screening and development of new therapeutic strategies for cancer and other diseases.
Biosafety:
II
Organism:
Mouse
Source Organ:
Embryo
Growth Properties:
Adherent
Morphology:
Polygonal
Clones:
N/A
Passage Number:
N/A
Population Doner:
N/A
Seeding Density:
Thaw entire contents into an appropriate T25 flask as specified in the Propagation instructions.
Markers:
N/A
Applications:
For Research Use Only
Doner Gender:
N/A
Donor Ethnicity:
N/A
Knockdown Method:
N/A
Induction:
N/A
Overexpression:
Transfected with wild-type Bcl-xL
Freeze Thaw:
N/A
Propagation:
The base medium for this cell line is Prigrow III medium available at abm
Preservation:
N/A
Quality Control:
1) Western blot analysis of Bcl-xL expression; 2) Microarray analysis
Tumorgenicn:
N/A
Shipping Conditions:
Dry Ice
Storage Contidions:
-180°C