Stauprimide | 1743

A cell-permeable analog of Staurosporine (Cat. No. 1048-010, 1) that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.

Stauprimide is a cell-permeable analog of Staurosporine (Cat. No. 1048-010, 1) that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.

1743 | Stauprimide DataSheet

Alternate Name/Synonyms: N-Benzoyl-7-oxostaurosporine

Appearance: Yellow orange solid

Formulation: N/A

CAS Number: 154589-96-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₅H₂₈N₄O₅

Molecular Weight: 584.62

Cell-Permeable?: Yes

Purity: ≥99% by HPLC

Solubilities: DMSO (100 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A stem cell differentiating agent

MDL Number: MFCD14635443

PubChem CID: 46245328

SMILES: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(=O)NC6=O)N(C)C(=O)C9=CC=CC=C9)OC

InChi: InChI=1S/C35H28N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16,23-24,31H,17H2,1-3H3,(H,36,40,41)/t23-,24-,31-,35+/m1/s1

InChi Key: MQCCJEYZKWZQHU-MPRCCEKMSA-N