Streptozocin | 1930

An antitumor antibiotic. Acts as a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Also acts as a diabetagen,and is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells. Streptozocin has been used to induce Type 1 diabetes for medical research.

Streptozocin is an antitumor antibiotic. Acts as a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Also acts as a diabetagen,and is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells. Streptozocin has been used to induce Type 1 diabetes for medical research.

1930 | Streptozocin DataSheet

Alternate Name/Synonyms: 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose

Appearance: White solid

Formulation: N/A

CAS Number: 18883-66-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₈H₁₅N₃O₇

Molecular Weight: 265.22

Cell-Permeable?: No

Purity: ≥95%

Solubilities: Water (100 mM)

Handling: Protect from moisture

Country of Origin: USA

Tag Line: An antitumor antibiotic and a DNA alkylating agent

MDL Number: MFCD00006607

PubChem CID: 7067772

SMILES: CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O

InChi: InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7, 12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7-/m1/s1

InChi Key: ZSJLQEPLLKMAKR-NYMZXIIRSA-N