Sucralfate | B2620

Sucralfate is a basic aluminum sucrose sulfate complex that displays gastroprotective activity. It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by pyloric ligation, indomethacin or cysteamine in rats. Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.

Sucralfate is a basic aluminum sucrose sulfate complex that displays gastroprotective activity. It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by pyloric ligation, indomethacin or cysteamine in rats. Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.

B2620 | Sucralfate DataSheet

Alternate Name/Synonyms: Sucrose octasulfate–aluminum complex, Sucrose Octasulfate Aluminium Salt

Appearance: White solid

Formulation:

CAS Number: 54182-58-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Molecular Weight: 2086.72

Cell-Permeable?: True

Purity: ≥95%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A gastroprotective agent

MDL Number: MFCD00145339

PubChem CID: 60196357

SMILES: O=S(OC[C@@H]1[C@@H](OS(=O)([O-][Al+3]2([OH-][Al+3]([OH-])([OH-])[OH-]2)[OH-])=O)[C@H](OS(=O)([O-][Al+3]3([OH-][Al+3]([OH-])([OH-])[OH-]3)[OH-])=O)[C@](COS(=O)([O-][Al+3]4([OH-][Al+3]([OH-])([OH-])[OH-]4)[OH-])=O)(O[C@@]5([H])O[C@H](COS(=O)([O-][Al+3]6([OH-][Al+3]([OH-])([OH-])[OH-]6)[OH-])=O)[C@@H](OS(=O)([O-][Al+3]7([OH-][Al+3]([OH-])([OH-])[OH-]7)[OH-])=O)[C@H](OS(=O)([O-][Al+3]8([OH-][Al+3]([OH-])([OH-])[OH-]8)[OH-])=O)[C@H]5OS(=O)([O-][Al+3]9([OH-][Al+3]([OH-])([OH-])[OH-]9)[OH-])=O)O1)([O-][Al+3]%10([OH-][Al+3]([OH-])([OH-])[OH-]%10)[OH-])=O

InChi: InChI=1S/C12H22O35S8.16Al.32H2O/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;;;;;;;;;;;;;;;;32*1H2/q;;;;;;;;;8*+1;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1................................................/s1

InChi Key: IRIPCXKKNOWLLY-PIPKHVHYSA-F