Description
Sucralfate is a basic aluminum sucrose sulfate complex that displays gastroprotective activity. It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by pyloric ligation, indomethacin or cysteamine in rats. Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.
Sucralfate is a basic aluminum sucrose sulfate complex that displays gastroprotective activity. It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by pyloric ligation, indomethacin or cysteamine in rats. Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.
Alternate Name/Synonyms: Sucrose octasulfate–aluminum complex, Sucrose Octasulfate Aluminium Salt
Appearance: White solid
Formulation:
CAS Number: 54182-58-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₅₄Al₁₆O₇₅S₈
Molecular Weight: 2086.72
Cell-Permeable?: True
Purity: ≥95%
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A gastroprotective agent
MDL Number: MFCD00145339
PubChem CID: 60196357
SMILES: O=S(OC[C@@H]1[C@@H](OS(=O)([O-][Al+3]2([OH-][Al+3]([OH-])([OH-])[OH-]2)[OH-])=O)[C@H](OS(=O)([O-][Al+3]3([OH-][Al+3]([OH-])([OH-])[OH-]3)[OH-])=O)[C@](COS(=O)([O-][Al+3]4([OH-][Al+3]([OH-])([OH-])[OH-]4)[OH-])=O)(O[C@@]5([H])O[C@H](COS(=O)([O-][Al+3]6([OH-][Al+3]([OH-])([OH-])[OH-]6)[OH-])=O)[C@@H](OS(=O)([O-][Al+3]7([OH-][Al+3]([OH-])([OH-])[OH-]7)[OH-])=O)[C@H](OS(=O)([O-][Al+3]8([OH-][Al+3]([OH-])([OH-])[OH-]8)[OH-])=O)[C@H]5OS(=O)([O-][Al+3]9([OH-][Al+3]([OH-])([OH-])[OH-]9)[OH-])=O)O1)([O-][Al+3]%10([OH-][Al+3]([OH-])([OH-])[OH-]%10)[OH-])=O
InChi: InChI=1S/C12H22O35S8.16Al.32H2O/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;;;;;;;;;;;;;;;;32*1H2/q;;;;;;;;;8*+1;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1................................................/s1
InChi Key: IRIPCXKKNOWLLY-PIPKHVHYSA-F
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |