Sulfasalazine | B2331

An anti-inflammatory agent and GST inhibitor. Sulfasalazine inhibits TNF-α and LPS-induced NF-κB activation in SW620 colon cancer cells. It also inhibits degradation of IκBα and prevents nuclear translocation of NF-κB induced by TNF-α.

Sulfasalazine is an anti-inflammatory agent and GST inhibitor. Sulfasalazine inhibits TNF-α and LPS-induced NF-κB activation in SW620 colon cancer cells. It also inhibits degradation of IκBα and prevents nuclear translocation of NF-κB induced by TNF-α.

B2331 | Sulfasalazine DataSheet

Alternate Name/Synonyms: 2-hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]-benzoic acid,NSC-667219,NSC-203730

Appearance: Light yellow to light brown solid

Formulation:

CAS Number: 599-79-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₈H₁₄N₄O₅S

Molecular Weight: 398.39

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: >25 mg/ml (DMSO) in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An anti-inflammatory agent and GST inhibitor

MDL Number:

PubChem CID: 5359476

SMILES: C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O

InChi: InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,20H,(H,19,22)(H,24,25)/b21-13-

InChi Key: OQANPHBRHBJGNZ-BKUYFWCQSA-N