Survivin Antibody | 3161

Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differentiated adult tissues. It has been shown that recombinant expression of Survivin conteracts apoptosis of B lymphocyte precursors deprived of interleukin 3 (IL-3), s?ggesting a potential role of Survivin in cancer therapy. Survivin interacts with the processed form of caspase-3 and inhibits its proteolytic activity.

3161 | Survivin Antibody DataSheet

Antibody Target: Survivin/TIAP

Target Alternative Name: BIRC5, IAP4 , API4, SVV , EPR-1

Tag Line:

Category: Surivivn

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: mouse

Immunogen Sequence: Synthetic peptide surrounding amino acids near the C-terminus of mouse survivin

Accession #: NP_033819

Gene ID: 11799

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.2 mg/ml

Formulation: 100 µg (0.2 mg/ml) affinity-purified rabbit anti-Survivin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified

Application: Western blot

Positive Control:

Application And Usages: Western blot analysis (0.5 - 2 µg/ml). However, the optimal conditions should be determined individually. The immunoaffinity purified antibody detects an approximately 17 kDa mouse survivin by Western blot analysis. Mouse spleen tissue lysate can be used as positive control.

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified