T-5224 | 9546

T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1 that ameliorates liver injury and improves survival through decreasing production of pro-inflammatory cytokines and chemokines in endotoxemic mice.

T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1 that ameliorates liver injury and improves survival through decreasing production of pro-inflammatory cytokines and chemokines in endotoxemic mice.

9546 | T-5224 DataSheet

Alternate Name/Synonyms: 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxybenzo[d]isoxazol-6-yl)methoxy)phenyl)propanoic acid

Appearance: Off-white solid

Formulation: N/A

CAS Number: 530141-72-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₉H₂₇NO₈

Molecular Weight: 517.53

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective inhibitor of c-Fos/activator protein (AP)-1

MDL Number: N/A

PubChem CID: 23626877

SMILES: C1CCC(C1)OC2=CC(=C(C=C2)C(=O)C3=CC(=C(C=C3)OCC4=CC5=C(C=C4)C(=O)NO5)CCC(=O)O)O

InChi: InChI=1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6,8-11,13-15,20,31H,1-4,7,12,16H2,(H,30,35)(H,32,33)

InChi Key: DALCQQSLNPLQFZ-UHFFFAOYSA-N