Description
T0070907 is a potent and selective antagonist of the human PPARγ (IC50 = 1 nM). T0070907 suppresses breast cancer cell proliferation and motility via both PPARγ-dependent and –independent mechanisms.
T0070907 is a potent and selective antagonist of the human PPARγ (IC50 = 1 nM). T0070907 suppresses breast cancer cell proliferation and motility via both PPARγ-dependent and –independent mechanisms.
Alternate Name/Synonyms: 2-Chloro-5-nitro-N-4-pyridinyl-benzamide
Appearance: White solid
Formulation: N/A
CAS Number: 313516-66-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₂H₈ClN₃O₃
Molecular Weight: 277.66
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (100 mM) or Ethanol (100 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective antagonist of the human PPARγ
MDL Number: MFCD00121849
PubChem CID: 2777391
SMILES: C1=CC(=C(C=C1[N+](=O)[O-])C(=O)NC2=CC=NC=C2)Cl
InChi: InChI=1S/C12H8ClN3O3/c13-11-2-1-9(16(18)19)7-10(11)12(17)15-8-3-5-14-6-4-8/h1-7H,(H,14,15,17)
InChi Key: FRPJSHKMZHWJBE-UHFFFAOYSA-Nv
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |