Description
T5601640, also known as T56-LIMKi, has high specific inhibitory activity for LIMK2 and shows little or no activity with LIMK1. It decreases levels of phosphorylated coflin (p-coflin) inhibiting several cancer cell lines including those of pancreatic cancer, gliomas and schwannoma.
T5601640, also known as T56-LIMKi, has high specific inhibitory activity for LIMK2 and shows little or no activity with LIMK1. It decreases levels of phosphorylated coflin (p-coflin) inhibiting several cancer cell lines including those of pancreatic cancer, gliomas and schwannoma.
Alternate Name/Synonyms: 3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide; T56-LIMKi
Appearance: White Solid
Formulation: N/A
CAS Number: 924473-59-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₄F₃N₃O₃
Molecular Weight: 389.33
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A specific LIMK2 inhibitor
MDL Number: NFCD08495674
PubChem CID: 9438169
SMILES: CC1=NOC(=C1)C(=O)NC2=CC=CC(=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F
InChi: InChI=1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27)
InChi Key: XVOKFRPKSAWELK-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |