T5601640 | B1097

T5601640, also known as T56-LIMKi, has high specific inhibitory activity for LIMK2 and shows little or no activity with LIMK1. It decreases levels of phosphorylated coflin (p-coflin) inhibiting several cancer cell lines including those of pancreatic cancer, gliomas and schwannoma.

T5601640, also known as T56-LIMKi, has high specific inhibitory activity for LIMK2 and shows little or no activity with LIMK1. It decreases levels of phosphorylated coflin (p-coflin) inhibiting several cancer cell lines including those of pancreatic cancer, gliomas and schwannoma.

B1097 | T5601640 DataSheet

Alternate Name/Synonyms: 3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide; T56-LIMKi

Appearance: White Solid

Formulation: N/A

CAS Number: 924473-59-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₁₄F₃N₃O₃

Molecular Weight: 389.33

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>15 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A specific LIMK2 inhibitor

MDL Number: NFCD08495674

PubChem CID: 9438169

SMILES: CC1=NOC(=C1)C(=O)NC2=CC=CC(=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F

InChi: InChI=1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27)

InChi Key: XVOKFRPKSAWELK-UHFFFAOYSA-N