TAK-700 | B2209

TAK-700 is a potent and highly selective human 17,20-lyase inhibitor (IC₅₀ = 38 nM). Displays >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Displays antiandogen activity.

TAK-700 is a potent and highly selective human 17,20-lyase inhibitor (IC₅₀ = 38 nM). Displays >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Displays antiandogen activity.

B2209 | TAK-700 DataSheet

Alternate Name/Synonyms: 6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methylnaphthalene-2-carboxamide; Orteronel

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 566939-85-3, 426219-18-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₇N₃O₂

Molecular Weight: 307.35

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and highly selective human 17,20-lyase inhibitor

MDL Number: N/A

PubChem CID: 9796590

SMILES: CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)C3(CCN4C3=CN=C4)O

InChi: InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22)/t18-/m0/s1

InChi Key: OZPFIJIOIVJZMN-SFHVURJKSA-N