Takinib | B2324

Takinib is a potent and selective TAK1 inhibitor (IC₅₀ = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases.

Takinib is a potent and selective TAK1 inhibitor (IC₅₀ = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases. Takinib is a potent and selective TAK1 inhibitor (IC50 = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases.

B2324 | Takinib DataSheet

Alternate Name/Synonyms: 3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide

Appearance: Crystalline solid

Formulation:

CAS Number: 1111556-37-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₈H₁₈N₄O₂

Molecular Weight: 322.36

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: >25 mg/ml (DMSO) in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective TAK1 inhibitor

MDL Number:

PubChem CID: 37750349

SMILES: CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N

InChi: InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)

InChi Key: UOZVVPXKJGOFIG-UHFFFAOYSA-N