Description
Takinib is a potent and selective TAK1 inhibitor (IC₅₀ = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases.
Takinib is a potent and selective TAK1 inhibitor (IC₅₀ = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases. Takinib is a potent and selective TAK1 inhibitor (IC50 = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases.
Alternate Name/Synonyms: 3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
Appearance: Crystalline solid
Formulation:
CAS Number: 1111556-37-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₈H₁₈N₄O₂
Molecular Weight: 322.36
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: >25 mg/ml (DMSO) in 0
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective TAK1 inhibitor
MDL Number:
PubChem CID: 37750349
SMILES: CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
InChi: InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
InChi Key: UOZVVPXKJGOFIG-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |