Description
A broad spectrum inhibitor of MMPs and ADAMs (proteins containing A Disintegrin and A Metalloprotease domain). This inhibitor has been used in tissue culture (typical concentration 5-100 μM).
TAPI-2 is a broad spectrum inhibitor of MMPs and ADAMs (proteins containing A Disintegrin and A Metalloprotease domain). This inhibitor has been used in tissue culture (typical concentration 5-100 μM).
Alternate Name/Synonyms: N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide; TNF protease inhibitor-0; C1
Appearance: White solid
Formulation: N/A
CAS Number: 187034-31-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₉H₃₇N₅O₅
Molecular Weight: 415.28
Cell-Permeable?: No
Purity: ≥95% by HPLC
Solubilities: H₂O (20 mM) and MeOH (5 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A broad spectrum inhibitor of MMPs and ADAMs
MDL Number: MFCD04119706
PubChem CID: 10093303
SMILES: CC(C)CC(CC(=O)NO)C(=O)NC(C(=O)NC(C)C(=O)NCCN)C(C)(C)C
InChi: InChI=1S/C19H37N5O5/c1-11(2)9-13(10-14(25)24-29)17(27)23-15(19(4, 5)6)18(28)22-12(3)16(26)21-8-7-20/h11-13,15,29H,7-10,20H2,1-6H3,(H,21, 26)(H,22,28)(H,23,27)(H,24,25)/t12-,13?,15+/m0/s1
InChi Key: LMIQCBIEAHJAMZ-RMTCENKZSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |