Description
Targocil is a novel antibiotic that inhibits a late acting step in the WTA (Wall teichoic acid) pathway. WTAs are phosphate-rich, sugar-based polymers attached to the cell walls of most Gram-positive bacteria. Targocil’s target is TarG, the transmembrane component of the ABC transporter (TarGH) that exports WTAs to the cell surface
Targocil is a novel antibiotic that inhibits a late acting step in the WTA (Wall teichoic acid) pathway. WTAs are phosphate-rich, sugar-based polymers attached to the cell walls of most Gram-positive bacteria. Targocil’s target is TarG, the transmembrane component of the ABC transporter (TarGH) that exports WTAs to the cell surface
Alternate Name/Synonyms: 3-((4-chlorophenyl)sulfonyl)-N,N-diethyl-7,8-dimethoxy-[1,2,3]triazolo[1,5-a]quinazolin-5-amine
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1200443-21-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₂ClN₅O₄S
Molecular Weight: 475.95
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A WTA (Wall teichoic acid) pathway inhibitor
MDL Number: N/A
PubChem CID: 44547009
SMILES: CCN(CC)C1=NC2=C(N=NN2C3=CC(=C(C=C31)OC)OC)S(=O)(=O)C4=CC=C(C=C4)Cl
InChi: InChI=1S/C21H22ClN5O4S/c1-5-26(6-2)19-15-11-17(30-3)18(31-4)12-16(15)27-20(23-19)21(24-25-27)32(28,29)14-9-7-13(22)8-10-14/h7-12H,5-6H2,1-4H3
InChi Key: TYNZGYMGTTUYKZ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |