TAS-301 | 9644

TAS-301 is an inhibitor of smooth muscle cell migration and proliferation. Blocks voltage-independent calcium influx and downstream PKC signaling. Inhibits neointimal thickening after balloon catheter injury to the rat common carotid artery. Inhibits calcium-dependent signal transduction and cytoskeletal reorganization.

TAS-301 is an inhibitor of smooth muscle cell migration and proliferation. Blocks voltage-independent calcium influx and downstream PKC signaling. Inhibits neointimal thickening after balloon catheter injury to the rat common carotid artery. Inhibits calcium-dependent signal transduction and cytoskeletal reorganization.

9644 | TAS-301 DataSheet

Alternate Name/Synonyms: 3-[Bis(4-methoxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one

Appearance: Yellow solid

Formulation: N/A

CAS Number: 193620-69-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₁₉NO₃

Molecular Weight: 357.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A smooth muscle cell migration and proliferation inhibitor

MDL Number: N/A

PubChem CID: 9885087

SMILES: COC1=CC=C(C=C1)C(=C2C3=CC=CC=C3NC2=O)C4=CC=C(C=C4)OC

InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H,1-2H3,(H,24,25)

InChi Key: KUEYYIJXBRWZIB-UHFFFAOYSA-N