Description
TASIN-1 (Truncated APC Selective INhibitor-1) is a novel truncated APC selective inhibitor, selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
TASIN-1 (Truncated APC Selective INhibitor-1) is a novel truncated APC selective inhibitor, selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
B2088 | TASIN-1 hydrochloride DataSheet
Alternate Name/Synonyms: 1'-[(4-Methoxyphenyl)sulfonyl]-4-methyl-1,4'-bipiperidine hydrochloride
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 1678515-13-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₂₉ClN₂O₃S
Molecular Weight: 388.95
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (~ 2 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A novel truncated APC selective inhibitor
MDL Number: N/A
PubChem CID: 132470901
SMILES: CC1CCN(CC1)C2CCN(CC2)S(=O)(=O)C3=CC=C(C=C3)OC.Cl
InChi: InChI=1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)16-9-13-20(14-10-16)24(21,22)18-5-3-17(23-2)4-6-18;/h3-6,15-16H,7-14H2,1-2H3;1H
InChi Key: TXDTUQPRRXNCLP-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |