Description
TBPB is a highly selective allosteric Muscarinic M1 agonist (EC₅₀ = 289 nM). TBPB increases non-amyloidogenic APP processing and produces antipsychotic-like effects in rodent models predictive of antipsychotic-like activity.
TBPB is a highly selective allosteric Muscarinic M1 agonist (EC₅₀ = 289 nM). TBPB increases non-amyloidogenic APP processing and produces antipsychotic-like effects in rodent models predictive of antipsychotic-like activity.
Alternate Name/Synonyms: 3-[1-[1-[(2-methylphenyl)methyl]piperidin-4-yl]piperidin-4-yl]-1H-benzimidazol-2-one
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 634616-95-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₃₂N₄O
Molecular Weight: 404.55
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly selective allosteric Muscarinic M1 agonist
MDL Number: MFCD22666590
PubChem CID: 10092649
SMILES: CC1=CC=CC=C1CN2CCC(CC2)N3CCC(CC3)N4C5=CC=CC=C5NC4=O
InChi: InChI=1S/C25H32N4O/c1-19-6-2-3-7-20(19)18-27-14-10-21(11-15-27)28-16-12-22(13-17-28)29-24-9-5-4-8-23(24)26-25(29)30/h2-9,21-22H,10-18H2,1H3,(H,26,30)
InChi Key: CWPKTBMRVATCBL-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |