TBPB | B1041

TBPB is a highly selective allosteric Muscarinic M1 agonist (EC₅₀ = 289 nM). TBPB increases non-amyloidogenic APP processing and produces antipsychotic-like effects in rodent models predictive of antipsychotic-like activity.

TBPB is a highly selective allosteric Muscarinic M1 agonist (EC₅₀ = 289 nM). TBPB increases non-amyloidogenic APP processing and produces antipsychotic-like effects in rodent models predictive of antipsychotic-like activity.

B1041 | TBPB DataSheet

Alternate Name/Synonyms: 3-[1-[1-[(2-methylphenyl)methyl]piperidin-4-yl]piperidin-4-yl]-1H-benzimidazol-2-one

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 634616-95-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₃₂N₄O

Molecular Weight: 404.55

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly selective allosteric Muscarinic M1 agonist

MDL Number: MFCD22666590

PubChem CID: 10092649

SMILES: CC1=CC=CC=C1CN2CCC(CC2)N3CCC(CC3)N4C5=CC=CC=C5NC4=O

InChi: InChI=1S/C25H32N4O/c1-19-6-2-3-7-20(19)18-27-14-10-21(11-15-27)28-16-12-22(13-17-28)29-24-9-5-4-8-23(24)26-25(29)30/h2-9,21-22H,10-18H2,1H3,(H,26,30)

InChi Key: CWPKTBMRVATCBL-UHFFFAOYSA-N