TC-H 106 | B1148

TC-H 106 is a class I Histone deacetylase (HDAC) inhibitor with IC₅₀ values of 150,370,760 and 5000 nM for HDAC1, 3, 2 and 8 respectively. TC-H 106 shows slow and tight binding inhibitory activity on class I HDACs and does not show inhibitory effect on class II HDACs.

TC-H 106 is a class I Histone deacetylase (HDAC) inhibitor with IC₅₀ values of 150,370,760 and 5000 nM for HDAC1, 3, 2 and 8 respectively. TC-H 106 shows slow and tight binding inhibitory activity on class I HDACs and does not show inhibitory effect on class II HDACs.

B1148 | TC-H 106 DataSheet

Alternate Name/Synonyms: N1-(2-Aminophenyl)-N7-(4-methylphenyl)heptanediamide

Appearance: Off-White Solid

Formulation: N/A

CAS Number: 937039-45-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₅N₃O₂

Molecular Weight: 339.43

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A class I Histone deacetylase (HDAC) inhibitor

MDL Number: MFCD17010287

PubChem CID: 16070100

SMILES: CC1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N

InChi: 1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25)

InChi Key: WTKBRPXPNAKVEQ-UHFFFAOYSA-N