Tetrahydrocurcumin | B2781

Tetrahydrocurcumin (THC) is a major metabolite of curcumin that displays antioxidant and anti-inflammatory properties. It has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress. THC is being studied for the treatment of cancer and dementia. THC is also known to epigenetically ameliorate mitochondrial dysfunction in brain vasculature during Ischemic Stroke.

Tetrahydrocurcumin (THC) is a major metabolite of curcumin that displays antioxidant and anti-inflammatory properties. It has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress. THC is being studied for the treatment of cancer and dementia. THC is also known to epigenetically ameliorate mitochondrial dysfunction in brain vasculature during Ischemic Stroke.

B2781 | Tetrahydrocurcumin DataSheet

Alternate Name/Synonyms: THC,NSC687845,1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione,Tetrahydrodiferuloylmethane

Appearance: White to off-white solid

Formulation:

CAS Number: 36062-04-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₄O₆

Molecular Weight: 372.41

Cell-Permeable?: TRUE

Purity: ≥95% by HPLC

Solubilities: ~5 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A major metabolite of curcumin

MDL Number: MFCD04152347

PubChem CID: 124072

SMILES: COC1=C(C=CC(=C1)CCC(=O)CC(=O)CCC2=CC(=C(C=C2)O)OC)O

InChi: InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3

InChi Key: LBTVHXHERHESKG-UHFFFAOYSA-N