Tetrahydropiperine | B2782

Tetrahydropiperine is a derivative of piperine (Cat. No. B2086) that displays various biological activities. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC50 = 6.3 µM). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50 = 23 µM) and 7-methoxycoumarin O-demethylase (MOCD) activity (IC50 = 25 µM) in rat liver microsomes.

Tetrahydropiperine is a derivative of piperine (Cat. No. B2086) that displays various biological activities. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC50 = 6.3 µM). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50 = 23 µM) and 7-methoxycoumarin O-demethylase (MOCD) activity (IC50 = 25 µM) in rat liver microsomes.

B2782 | Tetrahydropiperine DataSheet

Alternate Name/Synonyms: Tetrahydropiperine,5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpentan-1-one

Appearance: Crystalline solid

Formulation:

CAS Number: 23434-88-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₃NO3

Molecular Weight: 289.4

Cell-Permeable?: TRUE

Purity: ≥95%

Solubilities: ~10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A TRPV1 agonist

MDL Number:

PubChem CID: 581676

SMILES: O=C(CCCCC1=CC(OCO2)=C2C=C1)N3CCCCC3

InChi: InChI=1S/C17H23NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h8-9,12H,1-7,10-11,13H2

InChi Key: APZYKUZPJCQGPP-UHFFFAOYSA-N