Tetrandine | B2089

Tetrandrine is a bisbenylisoquinoline alkaloid that displays very broad pharmacological actions, including anti-tumor activity. It enhances the cytotoxicity of MDR-related drugs via modulation of P-gp. Also acts as a calcium channel blocker.

Tetrandrine is a bisbenylisoquinoline alkaloid that displays very broad pharmacological actions, including anti-tumor activity. It enhances the cytotoxicity of MDR-related drugs via modulation of P-gp. Also acts as a calcium channel blocker.

B2089 | Tetrandine DataSheet

Alternate Name/Synonyms: (4aS,16aS)-3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline; NSC 77037; d-Tetrandine

Appearance: Off-white solid

Formulation: N/A

CAS Number: 518-34-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₈H₄₂N₂O₆

Molecular Weight: 622.8

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A bisbenylisoquinoline alkaloid that displays very broad pharmacological actions

MDL Number: MFCD08689909

PubChem CID: 73078

SMILES: CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC

InChi: InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1

InChi Key: WVTKBKWTSCPRNU-KYJUHHDHSA-N