TG6-10-1 | 9646

TG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2. Displays low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors.

TG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2. Displays low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors.

9646 | TG6-10-1 DataSheet

Alternate Name/Synonyms: (E)-N-(2-(2-(trifluoromethyl)-1H-indol-1-yl)ethyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1415716-58-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₃F₃N₂O₄

Molecular Weight: 448.43

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective antagonist for the prostaglandin E2 receptor subtype EP2

MDL Number: N/A

PubChem CID: 71499384

SMILES: COC1=CC(=CC(=C1OC)OC)C=CC(=O)NCCN2C3=CC=CC=C3C=C2C(F)(F)F

InChi: InChI=1S/C23H23F3N2O4/c1-30-18-12-15(13-19(31-2)22(18)32-3)8-9-21(29)27-10-11-28-17-7-5-4-6-16(17)14-20(28)23(24,25)26/h4-9,12-14H,10-11H2,1-3H3,(H,27,29)/b9-8+

InChi Key: WUYOECAJFJFUFC-CMDGGOBGSA-N