26
Thioredoxin isoform 1 (Trx), Active, Human Recombinant | P1039
- SKU:
- 26-P1039-GEN
- Availability:
- Usually shipped in 5 working days
Description
Thioredoxin (Trx) is a disulfide reductase that reduces disulfide bonds into thiol groups through a thiol-disulfide exchange with its target proteins to regulate oxidative stress and redox signaling. Trx activity is dependent on NADPH and Thioredoxin Reductases (TrxR) ability to reduce it at Cysteine 32 and Cysteine 35.
P1039 | Thioredoxin isoform 1 Trx Active Human Recombinant DataSheet
Biomolecule/Target: Trx
Synonyms: TXN, TRX, TRX1, Thioredoxin 1
Alternates names: TXN, TRX, TRX1, Thioredoxin 1
Taglines: A protein involved in redox signaling
NCBI Gene ID #: 7043
NCBI Gene Symbol: TGFB3
Gene Source: Human
Accession #: P10600
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): Measured by its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
Biological activity: s recombinant human TGF-3 is fully biologically active when compared to standard. The ED determined by cytotoxicity assay using the world health organization standard 98/608 as a direct comparison is <0.05 ng/ml, corresponding to a specific activity of >2 x 10 units/mg.
Results: Enzymatic activity is 20 U/mg
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 14.5 kDa (130 aa)
Concentration: N/A
Appearance: Lyophilized
Physical form description: N/A
Reconstitution Instructions: This protein solution should be stored at 4°C, stable for at least 3 months. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA).
Amino acid sequence: N/A