Thioredoxin isoform 1 (Trx), Active, Human Recombinant | P1039

Thioredoxin (Trx) is a disulfide reductase that reduces disulfide bonds into thiol groups through a thiol-disulfide exchange with its target proteins to regulate oxidative stress and redox signaling. Trx activity is dependent on NADPH and Thioredoxin Reductase’s (TrxR) ability to reduce it at Cysteine 32 and Cysteine 35.

P1039 | Thioredoxin isoform 1 Trx Active Human Recombinant DataSheet

Biomolecule/Target: Trx

Synonyms: TXN, TRX, TRX1, Thioredoxin 1

Alternates names: TXN, TRX, TRX1, Thioredoxin 1

Taglines: A protein involved in redox signaling

NCBI Gene ID #: 7043

NCBI Gene Symbol: TGFB3

Gene Source: Human

Accession #: P10600

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): Measured by its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).

Biological activity: ’s recombinant human TGF-3 is fully biologically active when compared to standard. The ED determined by cytotoxicity assay using the world health organization standard 98/608 as a direct comparison is <0.05 ng/ml, corresponding to a specific activity of >2 x 10 units/mg.

Results: Enzymatic activity is 20 U/mg

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 14.5 kDa (130 aa)

Concentration: N/A

Appearance: Lyophilized

Physical form description: N/A

Reconstitution Instructions: This protein solution should be stored at 4°C, stable for at least 3 months. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA).

Amino acid sequence: N/A