Thrombospondin | 4806

Thrombospondin (TSP) is a cellular adhesion protein isolated from human platelets that had been stimulated with thrombin . TSP is a component of the coagulation mechanism and is believed to have potential as a marker for platelet activation and renal failure. Found in multiple biological processes including angiogenesis, apoptosis, activation of TGF- and immune regulation.

4806 | Thrombospondin DataSheet

Biomolecule/Target: N/A

Synonyms: Thrombospondin-1, THBS1, TSP, TSP1, THBS, THBS-1

Alternates names: Thrombospondin-1, THBS1, TSP, TSP1, THBS, THBS-1

Taglines: A secreted protein with antiangiogenic abilities

NCBI Gene ID #: 7043

NCBI Gene Symbol: TGFB3

Gene Source: Human

Accession #: P10600

Recombinant: No

Source: Human platelets

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: ’s recombinant human TGF-3 is fully biologically active when compared to standard. The ED determined by cytotoxicity assay using the world health organization standard 98/608 as a direct comparison is <0.05 ng/ml, corresponding to a specific activity of >2 x 10 units/mg.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 420.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from from 20 mM Tris-HCl, pH 8.0, with 600 mM NaCl, 2 mM CaCl, and 20% sucrose

Reconstitution Instructions: This protein solution should be stored at 4°C, stable for at least 3 months. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA).

Amino acid sequence: N/A