Description
Tideglusib is a potent, irreversible, non ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC₅₀ = 60 nM).
Tideglusib is a potent, irreversible, non ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC₅₀ = 60 nM).
Alternate Name/Synonyms: NP-12; NP031112; 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione
Appearance: White to of-white solid
Formulation: N/A
CAS Number: 865854-05-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₄N₂O₂S
Molecular Weight: 334.39
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, irreversible, non ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor
MDL Number: MFCD18633296
PubChem CID: 11313622
SMILES: C1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43
InChi: InChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2
InChi Key: PMJIHLSCWIDGMD-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |