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TLR2 Antibody (Clone BV31-9) | 3569
- SKU:
- 26-3569-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types are regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.
3569 | TLR2 Antibody (Clone BV31-9) DataSheet
Antibody Target: TLR2
Target Alternative Name: Toll-like receptor 2 , TLR2 , Anti-TLR2 , CD282 , TIL4
Tag Line:
Category: TLR
Host: Mouse
Isotype: Mouse IgG1
Species Reactivities: Human
Immunogen Sequence: Recombinant human TLR2
Accession #: O60603
Gene ID: 7097
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 100 µl protein G purified mouse anti-human TLR2 monoclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification:
Application: Western blot
Positive Control:
Application And Usages: Western blotting (1:200-1000 dilution). However, the optimal conditions should be determined individually. Ramos cell lysate can be used as a positive control and a ~86 kDa band is detected.
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |