Description
TM-5275 sodium salt is an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor. TM 5275 prolongs tPA retention and enhances plasmin generation on the vascular endothelial cell (VEC) surface as a result of PAI-1 inhibition.
TM-5275 sodium salt is an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor. TM 5275 prolongs tPA retention and enhances plasmin generation on the vascular endothelial cell (VEC) surface as a result of PAI-1 inhibition.
B1884 | TM-5275 Sodium salt DataSheet
Alternate Name/Synonyms: 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt
Appearance: White solid
Formulation: N/A
CAS Number: 1103926-82-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₈H₂₇ClN₃NaO₅
Molecular Weight: 543.98
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: An orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor
MDL Number: MFCD28396414
PubChem CID: 53240409
SMILES: C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)COCC(=O)NC4=C(C=C(C=C4)Cl)C(=O)[O-].[Na+]
InChi: InChI=1S/C28H28ClN3O5.Na/c29-22-11-12-24(23(17-22)28(35)36)30-25(33)18-37-19-26(34)31-13-15-32(16-14-31)27(20-7-3-1-4-8-20)21-9-5-2-6-10-21;/h1-12,17,27H,13-16,18-19H2,(H,30,33)(H,35,36);/q;+1/p-1
InChi Key: JSHSGBIWNPQCQZ-UHFFFAOYSA-M
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |