TNFSF18 polyclonal Antibody | BS61856

TNFSF18 polyclonal Antibody | BS61856 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: GITRL (glucocorticoid-induced TNF-related ligand), a polypeptide encoded by a human umbilical endothelial cell cDNA, is a member of the TNF (tumor necrosis factor) superfamily. GITRL has a type 2 transmembrane topology that is characteristic of the TNF family. The TNF superfamilies regulate diverse biological functions, including cell proliferation, differentiation and survival. GITRL is found on vascular endothelial cells and in several peripheral tissues (small intestine, ovary, testis and kidney), where it may modulate T lymphocyte survival. The GITR receptor recognizes GITRL and the two interact to regulate NFκB activation. The ligand-receptor pair of GITRL-GITR protects cells against AICD (activation-induced cell death) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TNFSF18 pAb detects endogenous levels of TNFSF18 protein.

Molecular Weight: ~ 22 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Tumor necrosis factor ligand superfamily member 18; Activation-inducible TNF-related ligand; AITRL; Glucocorticoid-induced TNF-related ligand; hGITRL

Immunogen: Synthetic peptide, corresponding Human TNFSF18.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: